Puerto Madryn is a city in the province of Chubut in Argentine Patagonia. It is the capital of the Viedma Department, and has about 93,995 inhabitants according to the last census in 2010.

Puerto Madryn is protected by the Golfo Nuevo, which is formed by the Península Valdés and the Punta Ninfas. It is an important centre for tourists visiting the natural attractions of the Península Valdés and the coast.

A new shopping mall in the city centre has helped tourism significantly, making Puerto Madryn a more attractive place for both international and domestic tourists visiting Patagonia. It is twinned with Nefyn, a small town on the Llŷn Peninsula in North Wales, the result of its enduring link with Welsh culture since the Welsh settlement in Argentina.